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mouse anti-exp1 and exp2  (European Malaria Reagent)

 
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    European Malaria Reagent mouse anti-exp1 and exp2
    High-resolution immunofluorescent identification of Plasmodium liver stage (LS) parasites. a High-resolution images of P . vivax hypnozoites demonstrate these forms have minimal nuclear material and are negative for schizogony markers EXP1, EXP 2 and MSP1. Hypnozoites stain positive for cytosolic markers MIF, HSP70, and GAPDH and reveal a functioning apicoplast. b By day 8, P . vivax schizonts are several times larger than the host cell hepatic nucleus, feature genome replication and segmentation, and stain positive for EXP1, <t>EXP2,</t> ACP, and MSP1. c The LS of P . falciparum is shorter than that of P . vivax schizonts; developing parasites are correspondingly less small. By day 5 merozoite segmentation has begun (as noted by ACP staining of separate apicoplasts) but not complete (as noted by diffuse staining of MSPs). d Immunofluorescent staining of day 8 P . vivax LS schizonts with anti-Pvs16, a sexual stage-specific biomarker for immature gametocytes, showed co-localization with developing LS merozoites indicated by segmented DNA. However, anti-Pvs16 signal does not appear in every LS. e The PHH system successfully supports complete maturation of Plasmodium LS schizonts measured by breakthrough into blood stage using reticulocyte ( P . vivax , days 9–11) or RBC ( P . falciparum , days 7–8) overlays with initial giemsa staining every 6 h. P . vivax overlays show formation of merozoite packages which rupture into the reticulocyte culture leading to invasion. Alternatively, no merosomes were captured in P . falciparum overlays but early rings were present within the first 12 h and continued culture progressed to an asynchronous population at > 1% parasitemia. White scale bars represent 5 µm, gray scale bars represent 10 µm
    Mouse Anti Exp1 And Exp2, supplied by European Malaria Reagent, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/mouse+anti-exp1+and+exp2/mouse+anti+exp2/pmc05943321-320-32-21
    Average 90 stars, based on 1 article reviews
    mouse anti-exp1 and exp2 - by Bioz Stars, 2026-09
    90/100 stars

    Images

    1) Product Images from "A comprehensive model for assessment of liver stage therapies targeting Plasmodium vivax and Plasmodium falciparum"

    Article Title: A comprehensive model for assessment of liver stage therapies targeting Plasmodium vivax and Plasmodium falciparum

    Journal: Nature Communications

    doi: 10.1038/s41467-018-04221-9

    High-resolution immunofluorescent identification of Plasmodium liver stage (LS) parasites. a High-resolution images of P . vivax hypnozoites demonstrate these forms have minimal nuclear material and are negative for schizogony markers EXP1, EXP 2 and MSP1. Hypnozoites stain positive for cytosolic markers MIF, HSP70, and GAPDH and reveal a functioning apicoplast. b By day 8, P . vivax schizonts are several times larger than the host cell hepatic nucleus, feature genome replication and segmentation, and stain positive for EXP1, EXP2, ACP, and MSP1. c The LS of P . falciparum is shorter than that of P . vivax schizonts; developing parasites are correspondingly less small. By day 5 merozoite segmentation has begun (as noted by ACP staining of separate apicoplasts) but not complete (as noted by diffuse staining of MSPs). d Immunofluorescent staining of day 8 P . vivax LS schizonts with anti-Pvs16, a sexual stage-specific biomarker for immature gametocytes, showed co-localization with developing LS merozoites indicated by segmented DNA. However, anti-Pvs16 signal does not appear in every LS. e The PHH system successfully supports complete maturation of Plasmodium LS schizonts measured by breakthrough into blood stage using reticulocyte ( P . vivax , days 9–11) or RBC ( P . falciparum , days 7–8) overlays with initial giemsa staining every 6 h. P . vivax overlays show formation of merozoite packages which rupture into the reticulocyte culture leading to invasion. Alternatively, no merosomes were captured in P . falciparum overlays but early rings were present within the first 12 h and continued culture progressed to an asynchronous population at > 1% parasitemia. White scale bars represent 5 µm, gray scale bars represent 10 µm
    Figure Legend Snippet: High-resolution immunofluorescent identification of Plasmodium liver stage (LS) parasites. a High-resolution images of P . vivax hypnozoites demonstrate these forms have minimal nuclear material and are negative for schizogony markers EXP1, EXP 2 and MSP1. Hypnozoites stain positive for cytosolic markers MIF, HSP70, and GAPDH and reveal a functioning apicoplast. b By day 8, P . vivax schizonts are several times larger than the host cell hepatic nucleus, feature genome replication and segmentation, and stain positive for EXP1, EXP2, ACP, and MSP1. c The LS of P . falciparum is shorter than that of P . vivax schizonts; developing parasites are correspondingly less small. By day 5 merozoite segmentation has begun (as noted by ACP staining of separate apicoplasts) but not complete (as noted by diffuse staining of MSPs). d Immunofluorescent staining of day 8 P . vivax LS schizonts with anti-Pvs16, a sexual stage-specific biomarker for immature gametocytes, showed co-localization with developing LS merozoites indicated by segmented DNA. However, anti-Pvs16 signal does not appear in every LS. e The PHH system successfully supports complete maturation of Plasmodium LS schizonts measured by breakthrough into blood stage using reticulocyte ( P . vivax , days 9–11) or RBC ( P . falciparum , days 7–8) overlays with initial giemsa staining every 6 h. P . vivax overlays show formation of merozoite packages which rupture into the reticulocyte culture leading to invasion. Alternatively, no merosomes were captured in P . falciparum overlays but early rings were present within the first 12 h and continued culture progressed to an asynchronous population at > 1% parasitemia. White scale bars represent 5 µm, gray scale bars represent 10 µm

    Techniques Used: Staining, Biomarker Discovery

    Related Articles

    Immunofluorescence:

    Article Title: A comprehensive model for assessment of liver stage therapies targeting Plasmodium vivax and Plasmodium falciparum
    Article Snippet: Briefly, the same immunofluorescence assay (IFA) protocol was followed above with the following fold dilutions of monoclonal antibodies obtained from The European Malaria Reagent Repository: mouse anti-GAPDH (Cat No. 7.2) at 1:50,000, mouse anti-EXP1and EXP2 (Cat No. 5.1 and 7.7) at 1:1000, mouse anti-GLURP (clones 22G6, 8B12, 2C7) at 1:200, anti-MSP1 (Cat No. 12.10) at 1:200, and anti-MSP2 (Cat No. 12.3) at 1:200 – .

    Bioprocessing:

    Article Title: A comprehensive model for assessment of liver stage therapies targeting Plasmodium vivax and Plasmodium falciparum
    Article Snippet: Briefly, the same immunofluorescence assay (IFA) protocol was followed above with the following fold dilutions of monoclonal antibodies obtained from The European Malaria Reagent Repository: mouse anti-GAPDH (Cat No. 7.2) at 1:50,000, mouse anti-EXP1and EXP2 (Cat No. 5.1 and 7.7) at 1:1000, mouse anti-GLURP (clones 22G6, 8B12, 2C7) at 1:200, anti-MSP1 (Cat No. 12.10) at 1:200, and anti-MSP2 (Cat No. 12.3) at 1:200 – .

    Staining:

    Article Title: A comprehensive model for assessment of liver stage therapies targeting Plasmodium vivax and Plasmodium falciparum
    Article Snippet: Briefly, the same immunofluorescence assay (IFA) protocol was followed above with the following fold dilutions of monoclonal antibodies obtained from The European Malaria Reagent Repository: mouse anti-GAPDH (Cat No. 7.2) at 1:50,000, mouse anti-EXP1and EXP2 (Cat No. 5.1 and 7.7) at 1:1000, mouse anti-GLURP (clones 22G6, 8B12, 2C7) at 1:200, anti-MSP1 (Cat No. 12.10) at 1:200, and anti-MSP2 (Cat No. 12.3) at 1:200 – .

    Biomarker Discovery:

    Article Title: A comprehensive model for assessment of liver stage therapies targeting Plasmodium vivax and Plasmodium falciparum
    Article Snippet: Briefly, the same immunofluorescence assay (IFA) protocol was followed above with the following fold dilutions of monoclonal antibodies obtained from The European Malaria Reagent Repository: mouse anti-GAPDH (Cat No. 7.2) at 1:50,000, mouse anti-EXP1and EXP2 (Cat No. 5.1 and 7.7) at 1:1000, mouse anti-GLURP (clones 22G6, 8B12, 2C7) at 1:200, anti-MSP1 (Cat No. 12.10) at 1:200, and anti-MSP2 (Cat No. 12.3) at 1:200 – .



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    mouse anti-exp1 and exp2  (European Malaria Reagent)
    90
    European Malaria Reagent mouse anti-exp1 and exp2
    High-resolution immunofluorescent identification of Plasmodium liver stage (LS) parasites. a High-resolution images of P . vivax hypnozoites demonstrate these forms have minimal nuclear material and are negative for schizogony markers EXP1, EXP 2 and MSP1. Hypnozoites stain positive for cytosolic markers MIF, HSP70, and GAPDH and reveal a functioning apicoplast. b By day 8, P . vivax schizonts are several times larger than the host cell hepatic nucleus, feature genome replication and segmentation, and stain positive for EXP1, <t>EXP2,</t> ACP, and MSP1. c The LS of P . falciparum is shorter than that of P . vivax schizonts; developing parasites are correspondingly less small. By day 5 merozoite segmentation has begun (as noted by ACP staining of separate apicoplasts) but not complete (as noted by diffuse staining of MSPs). d Immunofluorescent staining of day 8 P . vivax LS schizonts with anti-Pvs16, a sexual stage-specific biomarker for immature gametocytes, showed co-localization with developing LS merozoites indicated by segmented DNA. However, anti-Pvs16 signal does not appear in every LS. e The PHH system successfully supports complete maturation of Plasmodium LS schizonts measured by breakthrough into blood stage using reticulocyte ( P . vivax , days 9–11) or RBC ( P . falciparum , days 7–8) overlays with initial giemsa staining every 6 h. P . vivax overlays show formation of merozoite packages which rupture into the reticulocyte culture leading to invasion. Alternatively, no merosomes were captured in P . falciparum overlays but early rings were present within the first 12 h and continued culture progressed to an asynchronous population at > 1% parasitemia. White scale bars represent 5 µm, gray scale bars represent 10 µm
    Mouse Anti Exp1 And Exp2, supplied by European Malaria Reagent, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/mouse+anti-exp1+and+exp2/mouse+anti+exp2/pmc05943321-320-32-21
    Average 90 stars, based on 1 article reviews
    mouse anti-exp1 and exp2 - by Bioz Stars, 2026-09
    90/100 stars
    		  Buy from Supplier

    Image Search Results


    High-resolution immunofluorescent identification of Plasmodium liver stage (LS) parasites. a High-resolution images of P . vivax hypnozoites demonstrate these forms have minimal nuclear material and are negative for schizogony markers EXP1, EXP 2 and MSP1. Hypnozoites stain positive for cytosolic markers MIF, HSP70, and GAPDH and reveal a functioning apicoplast. b By day 8, P . vivax schizonts are several times larger than the host cell hepatic nucleus, feature genome replication and segmentation, and stain positive for EXP1, EXP2, ACP, and MSP1. c The LS of P . falciparum is shorter than that of P . vivax schizonts; developing parasites are correspondingly less small. By day 5 merozoite segmentation has begun (as noted by ACP staining of separate apicoplasts) but not complete (as noted by diffuse staining of MSPs). d Immunofluorescent staining of day 8 P . vivax LS schizonts with anti-Pvs16, a sexual stage-specific biomarker for immature gametocytes, showed co-localization with developing LS merozoites indicated by segmented DNA. However, anti-Pvs16 signal does not appear in every LS. e The PHH system successfully supports complete maturation of Plasmodium LS schizonts measured by breakthrough into blood stage using reticulocyte ( P . vivax , days 9–11) or RBC ( P . falciparum , days 7–8) overlays with initial giemsa staining every 6 h. P . vivax overlays show formation of merozoite packages which rupture into the reticulocyte culture leading to invasion. Alternatively, no merosomes were captured in P . falciparum overlays but early rings were present within the first 12 h and continued culture progressed to an asynchronous population at > 1% parasitemia. White scale bars represent 5 µm, gray scale bars represent 10 µm

    Journal: Nature Communications

    Article Title: A comprehensive model for assessment of liver stage therapies targeting Plasmodium vivax and Plasmodium falciparum

    doi: 10.1038/s41467-018-04221-9

    Figure Lengend Snippet: High-resolution immunofluorescent identification of Plasmodium liver stage (LS) parasites. a High-resolution images of P . vivax hypnozoites demonstrate these forms have minimal nuclear material and are negative for schizogony markers EXP1, EXP 2 and MSP1. Hypnozoites stain positive for cytosolic markers MIF, HSP70, and GAPDH and reveal a functioning apicoplast. b By day 8, P . vivax schizonts are several times larger than the host cell hepatic nucleus, feature genome replication and segmentation, and stain positive for EXP1, EXP2, ACP, and MSP1. c The LS of P . falciparum is shorter than that of P . vivax schizonts; developing parasites are correspondingly less small. By day 5 merozoite segmentation has begun (as noted by ACP staining of separate apicoplasts) but not complete (as noted by diffuse staining of MSPs). d Immunofluorescent staining of day 8 P . vivax LS schizonts with anti-Pvs16, a sexual stage-specific biomarker for immature gametocytes, showed co-localization with developing LS merozoites indicated by segmented DNA. However, anti-Pvs16 signal does not appear in every LS. e The PHH system successfully supports complete maturation of Plasmodium LS schizonts measured by breakthrough into blood stage using reticulocyte ( P . vivax , days 9–11) or RBC ( P . falciparum , days 7–8) overlays with initial giemsa staining every 6 h. P . vivax overlays show formation of merozoite packages which rupture into the reticulocyte culture leading to invasion. Alternatively, no merosomes were captured in P . falciparum overlays but early rings were present within the first 12 h and continued culture progressed to an asynchronous population at > 1% parasitemia. White scale bars represent 5 µm, gray scale bars represent 10 µm

    Article Snippet: Briefly, the same immunofluorescence assay (IFA) protocol was followed above with the following fold dilutions of monoclonal antibodies obtained from The European Malaria Reagent Repository: mouse anti-GAPDH (Cat No. 7.2) at 1:50,000, mouse anti-EXP1and EXP2 (Cat No. 5.1 and 7.7) at 1:1000, mouse anti-GLURP (clones 22G6, 8B12, 2C7) at 1:200, anti-MSP1 (Cat No. 12.10) at 1:200, and anti-MSP2 (Cat No. 12.3) at 1:200 – .

    Techniques: Staining, Biomarker Discovery